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Gliadin induced release of zonulin by binding to CXCR3 and elevated permeability ex vivo in biopsies of healthy volunteers and patients with quiescent CeD (90, 91)

While brief room-temperature handling for a few minutes is generally tolerated, exposures measured in hours should prompt a call to the dispensing pharmacy

The use of abdominal ultrasound in the detection of steatosis is an established methodology, and studies on HRT that employ abdominal ultrasound are likely to detect MASLD more reliably in their populations (131)